Showing posts with label Science. Show all posts
Showing posts with label Science. Show all posts

Monday, 21 October 2013

Guest Post - Elizabeth Bailey

Another blog post by one of my wonderful fellow ambassadors, and a real inspiration of mine, for you to enjoy today. Elizabeth is a wonderful lady, full of passion, intelligence and a real zest for life. I am honoured that she has allowed me to share some of her thoughts with you.

Elizabeth Bailey is Cancer Research UK’s Campaigns Ambassador for Luton South and on the Committee of CR UK Luton Relay for Life. Following a brush with breast cancer, she recently gave up a twenty-year Civil Service career and now combines being a postgraduate student with working in her local Public Health Team, and being a mum to two young daughters.  Elizabeth writes on cancer, and being a volunteer:

Over the past week, a family friend has been faced with the possibility that the breast cancer, for which she was successfully treated thirteen years ago, had returned, this time in her bones – secondaries, for which we know there is no cure.

The news stopped me in my tracks. Over time, I had come to the conclusion that the cancer for which I myself was treated three years ago was one of the best things that ever happened to me.  I’ll explain further why thought this, but for now, I’m having to consider that the life enhancing things which have come my way since then may have done so at some considerable cost – and only time will tell.

Early in 2010, I found myself sitting in a rain-drenched hospital car park howling with animal rage because I thought I would not see my little daughters grow up. But chemo, much surgery and radiotherapy have since been and gone.  It is now 2013, and the cancer, fingers crossed, is also gone.  But not the rage.  Cancer, in all its unpleasant incarnations, is now my chosen enemy. 

Everyone should have an enemy, don’t they say – it gives you purpose and direction, something to fight against. It did me. I now devote a good third of my time to helping dismantle this enemy, picking it apart bit by bit, with money, science, politics and the best efforts I can make to weaken it. I hope that even if it is still strong enough to take my friends, or even me, it will be a shadow by the time my daughters have to think about it. It’s in my sightline, and I’m proud to be called obsessive. One of my fellow CRUK Ambassadors, Jan Sheward, once vividly described to me her feeling of controlled rage about cancer.  Right on. I’m cool, calm, and armed with lots of facts and figures. Whoever wants to take me on, good luck.

Don’t misunderstand me - I respect my enemy, and it has given me things.  A whole host of new friends, for one.  Some really exciting, career-enhancing volunteering opportunities for another.  The courage to make a major change. Oh, and something to study for my PhD.  I really can’t complain about all of that. 
But there won’t be any gratitude. On Tuesday last week I went to the House of Commons with my fellow Ambassador Gower Tan, telling Peers and MPs why they should be playing their part in the further crowding-out of tobacco products by supporting an amendment to the Children and Families Bill.  This would enforce standardised cigarette packaging in shops where children are able to see those products. Yes, that’s right. Let’s not mess about here, the moral argument is won.  Peer-reviewed evidence proves that pack marketing attracts children. So we need to stop a toxic, addictive product, and the number one preventable cause of cancer, being dressed up in a completely misleading way. The game is over.  It’s now about taking timely action to save real people’s lives, and I will be making this very clear indeed.



We will win on this point.  It is not matter of if, but of when.  Funnily enough, until recently I used to rail against people describing cancer treatment as a ‘battle’, a ‘fight’ or a ‘war’. I had sad images of my old Dad, too weak to fight. But guess what - I’m getting over myself. If it helps some people to think like that, so be it.  Besides which, I think you can see I’m a bit of a street fighter myself - and I am not putting my coat back on just yet, not until I’m finished.

Wednesday, 4 September 2013

The Eve Appeal - Raising Awareness of Gynae Cancers



Happy Wednesday one and all!
 
Fifty three women are diagnosed with a gynaecological cancer every day in the UK and twenty one die. The Eve Appeal was launched in 2005 to raise awareness of these cancers as well as raise funds for research into these cancer types. 

I wanted to focus on The Eve Appeal today and shine a light on all that they do.
Gynaecological Cancer is the group term for five cancer types that originate in the female reproductive system:
*Cervical Cancer – cancer of the cervix (neck of the womb). I have written extensively about this cancer type. It can affect women of all ages but is commonly found in women aged between thirty and forty five. It is a largely preventable cancer type as I like to mention as much as possible. Key symptoms of cervical cancer are:
-Any unusual bleeding from the vagina particularly after sex and after the menopause
-Persistent vaginal discharge that is blood stained or smells unpleasant.
The UK has a very successful screening process for cervical cancer involving smear tests and this is estimated to save around four thousand lives every year. The HPV vaccine will hopefully lead to even more prevented cases of cervical cancer in the future but at the moment it is hugely vital that you have your regular smear tests to pick up on any abnormal cells and treat them before they develop into cervical cancer.

*Ovarian Cancer – cancer of the ovaries accounts for more deaths in the UK then the other four gynaecological cancers put together. Around six thousand five hundred women are diagnosed with ovarian cancer in the UK every year and around four thousand two hundred die. The symptoms of ovarian cancer are hard to identify and it can be hard to diagnose the condition until it has spread to other parts of the body but the key early signs of ovarian cancer are:
-persistent pelvic and abdominal pain
-Increased abdominal size/persistent bloating
-Difficulty eating and feeling full quickly
-Needing to urinate more frequently
These symptoms are not just indicators for ovarian cancer but should always be checked out by a doctor to rule out anything serious such as ovarian cancer.

*Vaginal Cancer – cancer of the vagina is very rare and there are about two hundred and fifty cases seen in the UK every year. It is rarely found in ladies under the age of forty but most commonly found in women over the age of sixty. Changes to the vaginal lining called Vaginal Intrapithelial Neoplasia (VAIN) can give you a higher chance of developing vaginal cancer although the changes are not enough to make cells cancerous on their own. Cervical screening can sometimes pick up on these changes but this is not guaranteed as cervical cells are sampled during a smear test rather then vaginal cells. The HPV vaccine is able to provide some protection against vaginal cell changes. Symptoms of vaginal cancer or VAIN are are but can include:
-intermenstrual bleeding or bleeding after the menopause
-bleeding after sex
-vaginal discharge with a strong odour or that is blood stained
-pain during sex
-A lump or growth in the vagina
-A vaginal itch that won’t go away
20% of women diagnosed with vaginal cancer do not have any of the above symptoms and most of the above symptoms can be caused by something else so it is hugely vital that you visit your doctor for a check up if you feel something isn’t quite right.

Vulva Cancer – Vulva is the term used for the female external genital organs and vulval cancer is another rare cancer type with just over a thousand UK women diagnosed yearly. Around 80% of the women diagnosed are aged over sixty but the precancerous condition Vulval Intraepithelial Neoplasia (VIN) can be found in women aged between thirty to fifty. Signs of vulva cancer can include:
-a lasting itch
-pain or soreness
-thickened, raised, red, white or dark patches of skin
-a sore of growth on the skin
-burning sensation when you urinate.
-vaginal discharge or bleeding
-a mole that changes shape or colour
-swelling or a lump
As with most symptoms, these ones can indicate something other than cancer of the vulva but it is still vitally important to get them checked by a doctor should they arise.

Womb Cancer – uterine or endometrial cancer is the fourth most common cancer found in UK women and changes in our lifestyles mean it is on the increase. It is almost always curable as long as it is found in the early stages. The key signs of womb cancer are:
-vaginal bleeding after the menopause
-intermenstrual bleeding.
Any abnormal bleeding should be investigated by your GP immediately to rule out anything life threatening.

The Eve Appeal works hard to fund world class research into these cancer types at the Department of Women’s Cancers which is based at UCH in London. The research benefits women across the world and The Eve Appeal are consistently contributing about 15% of the total income used for research. Major breakthroughs are being achieved and the research is pioneering new ways to screen for gynaecological cancers as well as diagnose them early, prevent and treat them. This all leads to thousands of lives being saved every year.

Ladies I cannot stress enough how important it is to get to know what is normal for your body, especially your reproductive system. By learning what is normal for you, you will be able to notice when something is not quite right and by working that out and visiting a doctor to get the abnormality checked, cancer can be diagnosed quicker. The earlier cancer is found, the easier it is to treat. MAKE SURE YOU HAVE REGULAR SMEARS TOO!!!

For more information on gynaecological cancers and The Eve Appeal, please visit. www.eveappeal.org.uk

This post is dedicated to my Auntie/Nouna Gina who died of ovarian cancer in September 1994. She is missed every day.

xxx

Friday, 30 August 2013

Cancer Research UK - Local Statistics



Happy Friday! A very quick post today!

The wonderful people at Cancer Research UK have created a way for you to find out the cancer statistics in your local area. It is a fantastic resource and I hope you find it useful and interesting!

http://www.cancerresearchuk.org/cancer-info/cancerstats/local-cancer-statistics/

Monday, 10 June 2013

Cervical Cancer Screening Awareness Week

Happy Monday!

This week is Cervical Screening Awareness Week and I wanted to use this opportunity to recover cervical cancer, the screening processes and what to do if you have an abnormal smear test.

CERVICAL CANCER IS PREVENTABLE!

I hope you find this post informative and interesting. Girls – please get your smears done regularly, it could save your life!

The Cervix:
The cervix is basically the neck of the womb (uterus). It is the opening to the womb from the vagina. The cervix is a very strong muscle which is usually tightly shut but it does open during labour so the baby can come out. The outer surface of the cervix has a layer of cells which are almost skin-like. When these cells become cancerous it is known as squamous cell cervical cancer. There are glandular cells lining the inside of the cervix producing mucus. Cancer of these cells is called adenocarcinoma of the cervix. There is an area of the cervix known as the transformation zone. This is around the opening of the cervix leading onto a narrow passageway that runs into the womb. This zone is where cells are most likely to become cancerous.

Risks and Causes of Cervical Cancer:
* Human Pampilloma Virus (HPV) is the most common and biggest cause of cervical cancer. HPV is passed on from person to person via sexual contact. There are many different types of HPV and not all of them cause cervical cancer. One type causes genital warts but not cervical cancer. However other types are considered high risk. These types can lead to cells in the cervix changing and becoming cancerous. Most women who have HPV and develop cervical cancer will have had other infections caused by HPV in the past. However, not every woman with HPV will develop cervical cancer.
* Smoking can lead to cervical cancer; women who smoke are more likely to develop this type of cancer then women that do not smoke.
* Taking the pill can also increase your risk but the reason for this is not yet known
* Women that have bore a large number of children also have a slightly higher risk as are women with a weakened immune system.

Symptoms:
Before I start listing the symptoms, please note that pre cancerous cells do not produce symptoms. This means having a smear test is hugely important – you can catch the cancer before it even develops. It is also important to know that the following symptoms do not instantly mean you have cervical cancer but it is important to go to your doctor if you have any of these symptoms:
* Bleeding between periods
* Bleeding during or after sex
* Bleeding at any time after the menopause
* Discomfort or pain during sex

Jo’s Cervical Cancer Trust
Jo’s Cervical Cancer Trust is also known as Jo’s Trust and it is the only UK based charity to focus solely on women that have been affected by cervical cancer and their families. They also help women dealing with cervical abnormalities. They aim to offer information, advice, friendship and support to these women, regardless of their age and status. They also try to educate women on the importance of cervical screening and to provide support for the women that have abnormal screening results or ladies that have a cervical cancer diagnosis.

Jo’s Trust has a mission: “Our mission is to see cervical cancer prevented, reduce the impact for everyone affected by cervical abnormalities and cervical cancer through providing the highest quality information and support services and campaigning for excellence in cervical cancer treatment and prevention."

The trust also has some core values and all the work they do is based around them. These qualities include remaining people focused, providing the highest quality, valuing and respecting others and empowerment.
The trust provides support groups, allowing women to come together, bond and share experiences. They also have a helpline to provide support, they have an online forum for people to come together in the comfort of their own home and a yearly meeting for women to get together and enjoy themselves. They also provide many helpful information leaflets which can be found on their website.

Jo’s Trust is a fabulous charity which does amazing things for women in the UK. I whole heartedly agree with their mission and their core values and I would love to see them succeed and help make cervical cancer a thing of the past. Please do check out their website and find out ways to help them achieve their goals. You can also find them on twitter @JosTrust

Smear Tests:
It is hugely important to have cervical screening as preventing cervical cancer from developing is vital. Cervical cancer is actually one of the only cancers that is preventable because if pre cancerous cells are detected through screening then they can be treated before they have a chance to become cancerous.
Women between the ages of twenty five and sixty are encouraged to have smear tests every three to five years to detect any changing cells in their cervix. During a smear test, a doctor or nurse will insert a speculum into your vagina and scrape anyway a sample of cells from your cervix. These cells are then placed into a small pot of liquid and send to be analysed. You will then be contacted with your results and any abnormal smears will require further investigation.

You don’t have to be over the age of twenty five to develop cervical cancer; some younger women do develop it as well. However, in the UK, smear tests are not encouraged until twenty five because your cervix is still developing in your teens and early twenties. This means the likelihood of you getting an abnormal result is more common but usually nothing to worry about. After Jade Goody’s horrifically young death, a campaign was launched to lower the smear test age limit but medical professionals do not agree with this. If you are under twenty five and are concerned about your cervical cancer risk – please do speak to your GP and get some advice. A private gynaecologist may allow you to have a smear test but it would depend on your individual circumstances.

PLEASE DO NOT BE SCARED TO HAVE A SMEAR TEST – THEY ARE UNCOMFORTABLE AND UNLADYLIKE BUT THEY DO SAVE LIVES! A FEW MINUTES OF DISCOMFORT IS BETTER THEN A BATTLE WITH CERVICAL CANCER!!!

It is also important to note that an abnormal smear result does not mean you have cervical cancer. If you are contacted and told your test was abnormal then please do not ignore it, go and see what your doctors have to say.

I’m approaching my twenty third birthday so I am not entitled to smear tests yet. I’ve heard horror stories about them and I am slightly worried about them. However, I will be forcing myself to attend my smear tests appointment when they are available to me. If I do develop pre cancerous cells – I will be finding them and I will be stopping them from developing.

Points to Consider:
You can have a smear test at several different places:
* Your GP’s surgery should offer them
* A family planning clinic
* A genito-urinary clinic
* An antenatal clinic
* A private health clinic
* Marie Stopes

You are well within your rights to request a female doctor or nurse performs your test but any male doctors will be chaperoned by a female staff member anyway. It is important to state if you require a female at the time of booking your appointment. 

A smear test should be scheduled whilst you are in the middle of your menstrual cycle (between periods) as it will be very difficult to see your cervix and get a cell sample whilst you are bleeding.

Age Limits:
There are varying age limits for women in the four nations of the UK.
* Women between the ages of twenty five and sixty four are screened every three to five years in England and Northern Ireland.
* In Scotland, cervical screening is offered to women aged between twenty and sixty.
* Wales offers cervical screening to women aged between twenty and sixty four.

Research has shown that screening every three years prevents 84/100 cases of cervical cancer that would develop if they weren’t caught by the smears. So getting a smear test every three years is recommended by the NHS up until you are fifty years old. Abnormal cells develop at a much slower rate in women over fifty so screening is recommended after five years for women in that age group. Your local primary care trust will contact you whenever it is time for a screening for you. I cannot stress the importance of attending these appointments enough – it could save you from a battle with cancer.


The Screening Process:
Cervical cancer is preventable. This is because pre cancerous cell changes can be picked up before they have a chance to develop. A cervical cancer screening test is known as a smear test. This involves a doctor or a nurse using a speculum to take a small sample of cells from the surface of your cervix. It sounds horrific and it can be very uncomfortable but I am going to try and explain it as clearly as I can!
You will need to take off your underwear and lie back on the couch/bed. Being as relaxed as you possibly can be will make the procedure less uncomfortable. 

Occasionally, the person doing the test will perform a vaginal examination first. This means they will place two gloved fingers inside your vagina to make sure your womb is in the correct position and that it feels like it’s a normal size. They will use their other hand to press down on your abdomen and gently feel your womb.

Then comes the actual smear test: The speculum is placed inside your vagina and has two arms which are used to spread the sides of your vagina apart so the cervix can be clearly seen. A small brush is then inserted and used scraped along the surface of your cervix to collect a sample of your cells. The brush and the cells are then sent to a lab in a pot of liquid and examined under a microscope. Any abnormal cells are reported and further investigation on these cells will be needed. 

The Results:
The important thing to remember with smear tests results is: DON’T PANIC!!! Cancer is not the only cause of abnormal cells or an abnormal result. Sometimes you may be asked to go back for a repeat test, again don’t panic, it could be because:
* You were on your period and the blood meant your cells weren’t visible enough
* Your cervix was inflamed and the cells weren’t visible enough
* An infection was blocking the view of the cells
* There were not enough cells collected in the first test

You may also be told that your test was borderline. This means cell changes have been noted but they were so very close to normal that they are probably nothing to worry yourself about and they will probably return to normal by themselves. You may be asked to go back and have another test in a few months to monitor the situation. You may also be offered a HPV test as HPV is a cause of cervical cancer. If you do test positive for HPV then you will probably been sent for more tests, including a colposcopy to monitor your cervix and the cell changes.

Cervical erosion can be picked up by smear tests. This is not cervical cancer. This means the glandular cells which are normally found inside your cervical canal are now visible on the surface of your cervix and it can be inflamed. This is a common condition for teenage girls, pregnant women and women on the pill. It can make you bleed slightly but it usually goes away by itself with no need for treatment.

Abnormal Tests Results:
Abnormal results are usually reported like this:

Mild Dyskaryosis or CIN 1(mild or slight cell changes)
If you are told that you have mild cell changes then you will probably be told to get a colposcopy straight away or to wait and have another smear in six months. Sometimes mild cell changes will go back to normal by themselves but it is important to monitor them and go back for any tests advised by your medical team. If a second test shows abnormal cells then a colposcopy is definitely needed to assess the situation. 


Moderate Dyskaryosis or CIN 2 (moderate cell changes)
Treatment will be needed if you have moderate cell changes but you only usually need it once. Then you will have follow up tests to monitor the cells in your cervix. If you have successful treatment after an abnormal smear and carry on having regular smears then you are unlikely to get cervical cancer. If you do not have treatment then you are at real risk of developing cervical cancer

Severe Dyskaryosis or CIN 3 (severe cell changes)
This is also sometimes known as carcinoma in situ (CIS) which sounds like cancer but it isn’t. This means some cells in your cervix look cancerous but are all found in the skin layer which covers your cervix. It won’t be “true” cancer until it breaks through the layer and starts to spread into the surrounding tissue. Urgent treatment is needed for this kind of smear result but if it is moved ASAP then cancer can be prevented.

All these results mean the cells found are pre cancerous meaning if they are left to go untreated, they could develop into cancer of the cervix. YOU DO NOT HAVE CERVICAL CANCER IF YOU ARE TOLD YOU HAVE ABNORMAL CELLS.

9/10 smears come back normal. 1/20 shows a borderline or mild cell change. Most of the time these cells will return to normal by themselves. 1/100 shows moderate cell changes whilst 1/200 show severe changes. Less than 1/1000 shows cancer. 

First Steps:
If you have mild cell changes then you may be told to wait six months and have a repeat test. This is because mild cell changes usually sort themselves out. If you have moderate to severe cell changes then you will probably be referred to your local hospital for a colposcopy. This is an outpatient procedure and it is basically a close examination of your cervix which doesn’t actually go inside your vagina. The doctor or nurse specialist uses something like a magnifying glass to look at the cells on your cervix in more detail and takes a biopsy to send to the lab for further examination.

Types of Treatment:
Laser Therapy (Laser Ablation): some cells can be burned away by a laser in an outpatient procedure. For this kind of treatment you will lie on a bed with your legs in stirrups whilst a doctor places a speculum into your vagina to hold it open whilst they point a laser beam at the abnormal areas. You will be given local anaesthetic to numb the area and prevent pain. The laser is a very strong and hot beam of light and it burns away the abnormal cells. This can cause a slight burning smell whist you are having the treatment but that just means the laser is working so try not to worry. You should be able to go home as soon as the treatment is finished. You may experience period type pains but they should go away with the normal paracetamol or ibuprofen and some bed rest.

Cold Coagulation: This name is a little misleading as the treatment isn’t cold at all! You lie on a bed with your legs in stirrups whilst a doctor inserts a speculum to hold your vagina open. A hot probe is then used to burn away the abnormal cells. You shouldn’t be able to feel the probe but it can cause some period type pains which should go away a few hours after the treatment has finished.

Cryotherapy: This is basically cold coagulation but with a cold probe instead of a hot one. The cold probe freezes the abnormal cells. The procedure is exactly the same as the cold coagulation.

Diathermy: This is done under local anaesthetic. An electronic current is used to cut away the tissue that contains the abnormal cells. It is a fairly quick procedure and it usually done as an outpatient case which means you should be able to go home afterwards. It can cause bleeding or discharge for about four weeks after the treatment but sanitary towels will have to be used as tampons have to be avoided for four weeks. Sex must also be avoided for four weeks following a diathermy procedure.

Cone Biopsy: This is a minor operation that can be used to diagnose cervical cancer or to treat abnormal cells. The entire area containing possible abnormal cells is removed. It is called a cone biopsy because a cone shaped area of tissue is removed from the cervix. This is called the transformation zone. This can be done under general or local anaesthetic.

Hysterectomy: If you are past menopause, or have had all your children, then your doctor may suggest removing your uterus. This is usually suggested if you have had abnormal cells more then once or if the cells are severely abnormal.

These treatments do sound rather uncomfortable and scary but it is massively important to have abnormal cells treated to prevent them developing into cervical cancer. Please do remember to book yourself in for a smear if you are due one. As I’ve said before, a little discomfort is nothing compared to a battle with cervical cancer.

HPV Vaccines
Some cervical cancer cases are caused by the human papilloma virus (HPV) which is also sometimes known as genital warts or the wart virus. There are over one hundred different types of HPV and some cause genital warts. Lots of types of HPV are passed on through sexual contact and most women will be affected by HPV at some point. Most of the time the virus will just go away with no treatment but some types can increase your risk of developing cervical cancer.  HPV types sixteen and eighteen cause about 70% of cervical cancer cases, which is roughly about 7/10 and most of the other 30% are caused by other high risk types of HPV.

Extensive research into HPV has been done over the years and two cervical cancer vaccines have been created. These are celled Gardasil and Cervarix. Research is on-going into these vaccines and their effects will become clearer as time goes on but here is some information on the two vaccines:

Trials have been done with Gardasil, using women between the ages of sixteen and twenty six. Some were given the vaccine and some were given placebos. They were all monitored to see if they went on to develop HPV. Research has shown that Gardasil protects against some types of HPV including types sixteen and eighteen. Since then Gardasil has been given a licence in the UK and can be used on young girls and women between the ages of nine and twenty six.

Cervarix has also gone through rigorous trials involving women under the age of twenty six. They discovered that Cervarix can prevent HPV. It has also been licenced for use in the UK and is used to prevent pre cancerous cervical changes in women between the ages of ten and twenty five.

UK schoolgirls aged between twelve and thirteen (year eight at secondary school are currently being offered the Cervarix vaccine as part of the HPV vaccination programme. This involved the girls having three injections over a six month period. Their parents have to sign a consent form before their daughter can have the vaccinations and they should discuss the vaccine with their daughter so she can decide whether or not she would like it. From September 2012 the vaccination programme will switch to the Gardasil vaccine as this protects them against genital warts as well as cervical cancer. It is also possible to have the vaccination done privately should you wish to do so.

The vaccines are given to twelve year olds because they are unlikely to have already become sexually active and caught HPV. Research has shown that the vaccine works best in younger women. You can still have the vaccine if you are already sexually active; it won’t get rid of HPV if you already have it but it can protect you from developing other types of the infection. It may be worth having if the type you have isn’t type sixteen or eighteen as these are the two that are most likely to cause cervical cancer. It is vital to have all three injections to make sure you are properly vaccinated.

Side effects of the vaccine are usually very mild but they can include:
Headaches and aching muscles, dizziness, fever, diarrhoea stomach pains and itching and soreness around the injection area.

IT IS IMPORTANT TO REMEMBER THAT YOU STILL NEED TO HAVE REGULAR SMEAR TESTS WHEN YOU REACH THE MINIMUM AGE REQUIRED. WHILST A VACCINE WILL HELP PROTECT YOU, SCREENING IS STILL NEEDED!!

If you are interested in having a cervical cancer vaccination – please contact your GP or Jo’s Trust.

I hope this blog post has given you all the facts. I hope it has persuaded you to have a smear test if you haven’t already.


xxx