I mentioned the most common type of
bone sarcoma yesterday. Osteosarcoma is most commonly found in the arm of leg
(specifically the thigh or shin bone) and is usually found in young people or
the very elderly.
The next most common form of primary
bone cancer is Ewing’s sarcoma, which I have written about previously. This can
affect any bone but is most commonly found in the pelvis, thigh and shin bone.
Ewing’s sarcoma is commonly found in teenagers and is very rare in those over
the age of thirty.
There are other types of bone
cancers that affect adults more then children for example histiocytome affects
connective tissue and chondrosarcoma originates in the cartilage.
Rarer types of bone cancer are Chordoma
which forms in the spine in adults and giant cell tumour (GIST) which can
affect any age.
Treating Bone Sarcomas:
The initial aim of treatment would be to remove the tumour
completely but the approach would depend on the type of bone cancer, for example
osteosarcoma is usually treated with high dose chemo before and possibly after
surgery whilst Ewing’s sarcoma responds well to radiotherapy in most cases so
that may also be included in the treatment plan.
Chondrosarcoma does not normally
respond well to chemo so surgery is usually the main treatment option for this
type of bone cancer.
Amputation is an option but is not considered lightly and is no
longer commonly used to treat bone cancer. Limb salvage techniques are used in
most cases should it be possible.
New
drugs are developed all the time to help patients with certain kinds of bone
tumours. Mifamurtide can be given to patients with osteosarcoma after surgical
chemotherapy and clinic trials have shown an improvement in long term survival.
England
has some specialist treatment centres for bone sarcoma:
*Newcastle
Upon Tyne Hospital NHS Foundation Trust
*Robert
Jones and Agnes Hunt Hospital
*Birmingham
Royal Orthopeadic NHS Trust
*Nuffield
Othopaedic Centre NHS Trust
*Royal
National Orthopaedic NHS Trust Stanmore
Scotland's managed sarcoma network has three centres for surgery
for bone tumours - Aberdeen, Glasgow and Edinburgh. Chemotherapy may be
provided in Inverness or Dundee if one of these is closer to the patient's
home.
In Wales it is most likely that a patient diagnosed with a primary
bone cancer will be referred to Birmingham for surgical treatment, although
chemotherapy may be provided closer to home.
For patients in Northern Ireland a referral to Birmingham is also
the favoured routine for treatment
Evidence appears to show that these specialist treatment centres
deliver the best results for patients and these centres are leaders in the
development of new techniques for bone tumours to try and avoid amputation whilst
improving survival rates.
I hope you have found this blog post informative, please contact
Sarcoma UK if you have any questions or are worried about anything you have
read here today
xxx
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